At least six of her relatives in New Jersey and Pennsylvania contracted the virus, NJ.com reported.
The relatives include five of Fusco-Jackson's siblings and their mother, according to their sister, Elizabeth Fusco.
Meanwhile, Fusco's eldest son, Carmine Fusco, also died from the virus at a hospital in Pennsylvania earlier Wednesday, Fodera told the paper.
Four other family members are at CentraState Medical Center, NJ.com reported.
One of the siblings is a friend of John Brennan, a horse trainer who was the first New Jersey resident to die from COVID-19.
The deaths have only added to the heartbreak of an already devastated family, Paradiso Fodera said.
Rita Fusco-Jackson died March 14 at CentraState Medical Center in Freehold Township but her death was not announced until days later, when her test result came back positive.
'This has been devastating for all of us, ' she told NJ Advance Media. "Our hearts are broken over losing our sister, Rita".
The exposures may have originated at a family event, she said.
"To imagine a week ago to get a phone call like this - if someone told me this story, I wouldn't believe it", she said.
Nineteen spouses and children of the hospitalized victims - who were in contact with them since March 10 - have been tested for the bug and are in isolation at their homes. New Jersey 101.5 was unable to reach Fusco on Wednesday for more information.
He had multiple underlying health conditions, including diabetes, high blood pressure and emphysema, putting him at higher risk of death.
Worldwide, more than 217,000 people have been infected and more than 8,900 people have died. "That confirmed case had a nexus with a confirmed case in Bergen County".