"This means, with these two authorized vaccines, we have already secured an amount of doses that we need to vaccinate 380 million Europeans", von der Leyen said.
There are hundreds still in development, with some expected to report findings in the near future.
Moderna Inc on Monday said it will produce at least 600 million doses of its COVID-19 vaccine.
That figure includes nearly a quarter of those aged over 80 in England - people at highest risk of severe illness or death from the virus.
The prime minister has said the aim is to vaccinate 15 million people in the United Kingdom by mid-February, including care homes residents and staff, frontline NHS staff, everyone over 70 and those who are clinically extremely vulnerable.
The move would allow European Union governments to double their orders from Pfizer to 600 million doses, commission president Ursula von der Leyen said, as the 27-nation bloc races to ramp up the vaccination of its 450 million people.
The additional doses will be delivered starting in the second quarter (Q2) of 2021, with 75 million being available in Q2 and the rest in Q3 and Q4.
"Having just received some additional data, we are now expecting the AstraZeneca file to be submitted next week, with a possible conclusion by the end of January", said Cooke during an online public stakeholder meeting.
"It is a proven vaccine - so the whole procedure of authorization is done". Instead, they use a piece of genetic code that trains the immune system to recognize the spike protein on the surface of the virus, ready to attack if the real thing comes along.
It requires temperatures of around -20C for shipping - similar to a normal freezer.
The AstraZeneca jab is easier to store and distribute, as it can be kept at normal fridge temperature.
The scams are preying on concerns about the far slower-than-promised rollout of vaccines to protect against the virus that has claimed more than 1.8 million lives worldwide so far. "It is a testament to the efforts and commitment of all involved that we have this second positive vaccine recommendation just short of a year since the pandemic was declared by World Health Organization". For all of the Covid vaccines, we still do not know how long immunity will last.
Moderna vaccine is the second to be approved by the European Medicines Agency.
The biotechnology company's chief executive officer said: "The nightmare scenario that was described in the media in the spring with a vaccine only working a month or two is, I think, out of the window".