The 74-year-old was hospitalised on July 1 after he tested positive.
"My friend Herman Cain, a Powerful Voice of Freedom and all that is good, passed away this morning".
He was treated in 2006 for colon cancer, which may have increased his risk of complications from Covid-19.
Im social media accounts bin dey give regular updates on im condition.
"Dis na tough virus", na wetin di post tok "please continue to pray".
A co-chair of Black Voices for Trump, Cain vocally sided with the president in his skepticism over the danger posed by the virus and the usefulness of facemasks.
The Twittersphere had lost no time blaming Trump for being at least partly responsible for Cain's illness by holding his campaign rally in Tulsa without a mask, thereby setting the example for Cain to do the same, insisting he had caught the coronavirus at the Tulsa rally.
Dem born am for Tennessee and im papa work as janitor, chauffeur and barber, and im mama work as servant, Oga Cain get degree for maths and masters for computing.
Im work as a Baptist minister, radio talk show host and as a businessman.
Cain held a string of corporate executive positions throughout his life, most prominently from 1986 to 1996 as president and chief executive of Godfather's Pizza, a national chain that he transformed into a success after it had been teetering on the brink of bankruptcy.
"And when dem ask me who be di president of Ubeki-beki-beki-beki-stan-stan, I go say you know, I no know".
Im bin dey popular for di beginning but later im come find imself inside plenty sexual harassment allegations. He suspended his campaign a month later.
The funeral service for civil rights icon Rep. John Lewis was televised on all the major channels today, featuring moving eulogies from three former presidents, George W. Bush, Bill Clinton, and Barack Obama, all of whom earned praise for their warm words. Last year, the president nominated Cain to a seat on the Federal Reserve Board, the USA central bank, but Cain withdrew after opposition mounted against him.
"Saddened that Herman Cain - a formidable champion of business, politics and policy - has lost his battle with Covid", Romney said.