European markets closed mixed, London's FTSE fell 0.9 per cent, Paris lost 0.2 per cent and Frankfurt closed 0.6 per cent higher. Enjoying a staggering 14.5% gain since January 1, it is easy to see the Nasdaq's leadership in the demand for risk exposure.
Markets closed higher on Tuesday to finish out the second quarter on a high note, despite soaring coronavirus cases and enormous economic uncertainty.
Oil prices went backwards, with Brent crude falling sharply (-1.4pc) to $US41.14 per barrel - as traders cashed in their recent profits, and Libya's state oil company flagged progress in talks to resume exports, potentially boosting global supply.
The S&P 500 and Dow Jones indexes opened lower on Tuesday as coronavirus-related worries and simmering US-China tensions weighed on sentiment at the end of what is expected to be the S&P 500's best quarter since 1998.
Kicking off a data-heavy week for Wall Street, figures on Tuesday showed US consumer confidence increased much more than expected in June.
The tech-heavy Nasdaq jumped 1.9 per cent - and posted its best quarter since 1999 (after surging by 30.6 per cent in the last three months).
At 11:11 a.m. ET, the Dow Jones Industrial Average was up 60.79 points or 0.24% at 25,656.59, the S&P 500 was up 23.34 points or 0.76% at 3,076.58, and the Nasdaq Composite was up 108.17 points or 1.10% at 9,982.33.
"Consumers are less pessimistic about the short-term outlook, but do not foresee a significant pickup in economic activity", said Lynn Franco, senior director of economic indicators at the Conference Board.
Dr Fauci also warned the virus spread "could get very bad", a reminder that a full economic recovery could be a long road.
"This doesn't improve Hong Kong's status as a financial centre, to say the least, coming back from the protests and the virus over the a year ago", said Ilan Solot, foreign exchange strategist at Brown Brothers Harriman in London.