Brazil surpassed 30,000 deaths from the coronavirus outbreak as the disease continued to rip through Latin America, while Italy - at one point the hardest-hit country - prepared to reopen its borders in time for the European summer.
There has also been scepticism in Russian Federation, where Moscow shopping malls and parks reopened on Monday despite the still-high number of cases. Cases across the country multiplied by five across the month of May, according to Brazil's Health Ministry.
Pupils wearing face masks returned to schools in Singapore and some workplaces re-opened as restrictions were eased Tuesday in the Asian city-state. Shopkeepers were eager to see business pick up again.
Russia's President Vladimir Putin meanwhile called Armenia's Prime Minister Nikol Pashinyan to wish him a speedy recovery, as he became the latest leader to test positive.
Slovenes enjoyed a fly-over by USA and local military jets to mark the "end of the pandemic" and to thank frontline health workers.
In Romania, excited families queued for the reopening of Bucharest's Grigore Antipa Natural History Museum.
The claim by Alberto Zangrillo, head of the San Raffaele Hospital in Milan, that the virus "no exists in Italy", was quickly challenged by experts in Italy and overseas. The worst of the pandemic has not yet come to Brazil, according to World Health Organization executive director Michael Ryan said on Monday.
Data compiled by John Hopkins University (USA) point out that the country is now the second in the number of Covid-19 records, behind only the USA, which adds up to nearly 1.8 million cases.
The country also registered 12,247 new confirmed cases.
France registered 31 deaths over the last 24 hours and on Tuesday re-opened cafes, restaurants and bistros that have been closed since its lockdown began in mid-March.
There were also snippets of inspiration however among the reams of bad news.
In South Africa, scores of joyous people blasting music queued outside liquor stores in the Johannesburg township of Soweto, waiting to stock up after a nine-week ban on alcohol sales ended. "This place is jamming", said one customer, Bongani Khumalo.
The pandemic has devastated the global economy, which is facing its worst downturn since the Great Depression.
With businesses and citizens growing exhausted of confinement, pressure is building on national leaders to end the lockdowns, especially in countries where the outbreak appears to be slowing.
But health experts continue to warn of a possible second wave of infections if authorities and citizens let their guard down.
The government of President Jair Bolsonaro has resisted social distancing efforts throughout the pandemic, with Mr Bolsonaro often mingling with supporters and pushing for people to get back to work to ease the economic fallout of the crisis.
The region has logged one million cases and recorded more than 50,000 deaths, with Brazil accounting for more than half of those cases and close to 60 percent of the fatalities.
In the United States - the worst-affected nation in the world, and now faced with a wave of street protests against police killings of unarmed black suspects - Washington and Los Angeles resumed outdoor dining, while New York City is on track to begin reopening from June 8.
The World Health Organisation meanwhile insisted it still wanted to keep working with the United States, despite President Donald Trump's decision last week to cut ties with the organisation.