Men who are more physically active may have a lower risk of developing prostate cancer, according to a study that relied on a cutting-edge form of genetic analysis to reach this conclusion, MedicalNewsToday reports.
The consultation encouraged consumption of at least seven daily servings of vegetables or fruit - defined as a half-cup of raw or cooked vegetables or fruits or 100 percent vegetable juice, including at least two servings each of cruciferous vegetables, like cabbage, and tomatoes.
"One of the most common questions I get from patients is:" Are there dietary changes I can make to combat cancer? ", Study co-author J. Kellogg Parsons, urology professor at Moores UC San Diego Extensive cancer center, UPI said".
The team says that trials showing the effectiveness of vegetable enriched diets in slowing disease progression would justify the development of behavioral interventions encouraging prostate cancer patients to adopt such diets. "Nevertheless, we also demonstrated - for the first time - that a simple, inexpensive, and convenient behavioral intervention can lead patients with prostate cancer to make healthier food choices".
To investigate whether a behavioral intervention created to increase micronutrient-enriched vegetable intake among men with early-stage prostate cancer was effective at preventing disease progression, Parsons and team conducted a phase 3 study called The Men's Eating and Living (MEAL) Study. A total of 226 of the subjects received the nutrition consultation, while the remaining 217 participants only received written information about diet and prostate cancer.
During the two-year study period, 245 study participants had their cancer progression, with a relatively equal distribution in both groups - 124 or 55 percent in the nutritional intervention group and 121 or 56 percent in the control group.
Researchers at the University of Bristol and Imperial College London in the United Kingdom employed a method known as Mendelian randomization that permitted them to analyze genetic variations between individuals to identify associations between potential risk factors and prostate cancer. Blood tests revealed that those in the dietary intervention group also had roughly 25 percent higher levels of plasma carotenoid - a biomarker for vegetable intake - than those in the control group.
"Diet is not a "magic bullet" for prostate cancer treatment", Parsons said. "But it's also worth noting that while a healthy diet rich in fruits and vegetables may not cure cancer, it will likely keep the body stronger and healthier, which may help patients better tolerate cancer treatments".