The cut didn't deter Inoue for most of the next five rounds as the two fighters traded punches left and right.
Pound-for-pound recognised star Inoue has blasted his way to world titles in three divisions and came in bang on the 118lbs limit, with his Filipino foe slightly under.
Watch Naoya Inoue against Nonito Donaire in the World Boxing Super Series Final, from 12.05pm on Thursday on Sky Sports Action and Sky Sports Mix.
This fight is widely considered an old lion versus the young lion, but Nonito feels he will be able to test Inoue's chin and knows he could also taste the canvas if he isn't careful. He won the 10th round, again effectively scoring with the jab and the straight right hand, as it looked as though Donaire was wearing out. Donaire then staggered Naoya Inoue with a big left hand in the ninth round, but Inoue smartly used his head movement to avoid any further trouble.
Donaire got up at the count of 9, but was clearly tired and Inoue battered him with several more punches and was on the verge of maybe scoring a TKO.
Inoue wins the World Boxing Super Series tournament that began with eight fighters a year-and-a-half ago.
As for Inoue's own future, he'll likely be heading stateside as he has reportedly signed a multi-fight deal with Top Rank Boxing and is expected to fight in the United States in 2020.
In addition to the prestige of the Muhammad Ali Trophy, Inoue also collects over a $1 million purse bonus for having captured the WBSS championship.