The wall divided East and West Berlin from 1961 to 1989, with the German Democratic Republic (controlled by the Soviet Union) ruling the east, and the Federal Republic of Germany (overseen by an allied coalition of Britain, France, and the U.S.) ruling the west.
But unlike the optimism at previous commemorations of the epochal event on November 9, 1989 that brought the communist regime crashing down, three decades on, the mood has soured as the Western alliance that helped secure the liberal democracy is riddled with divisions.
"The Berlin Wall, ladies and gentlemen, is history and it teaches us: No wall that keeps people out and restricts freedom is so high or so wide that it can't be broken down".
Speaking on Saturday, President Frank-Walter Steinmeier paid tribute to Germany's neighbours, saying: "Without the courage of the will to freedom of the Poles and Hungarians, the Czechs and Slovaks, the peaceful revolutions in Eastern Europe and Germany's reunification would not have been possible".
"The values on which Europe is founded - freedom, democracy, equality, the rule of law, respect for human rights - are anything but self-evident", she said, adding that such values "must be defended again and again". "That's why Germany and its European allies had to fight every day for a peaceful and united Europe with each country having to do its part to overcome differences".
Pompeo meanwhile left behind a stark warning: "As we celebrate, we must also recognise that freedom is never guaranteed". And to all those who doubt that democracy, even with its difficulties and imperfections, offers the best way for free men and women to pursue happiness and reach for opportunity, we say once more: "'Let them come to Berlin'".
"She also recalled that November 9 remains a fraught date in German history, as it also marks the anniversary of the so-called Night of Broken Glass, an anti-Jewish pogrom in 1938 that foreshadowed the Nazi's Holocaust.Light installations, concerts and public debates were planned throughout the city and other parts of Germany to mark the fall of the Wall, including a concert at Berlin's iconic Brandenburg Gate".
The Soviets eventually erected an "Iron Curtain" splitting the East from the West.
"That applies to us all in East and West: we stand stripped of any excuses and are required to do our part for freedom and democracy".
"I congratulate the German people on the tremendous strides that have been made in reuniting their country and in rebuilding the former East Germany". The barbed wire and concrete structure had divided East from West Berlin. Border guards eventually opened the barriers - leading to thousands rushing through, and breaking the wall with hammers and pickaxes.