During a meeting with Chairperson of the African Commission on Human and Peoples' Rights (ACHPR) Commissioner Soyata Maiga on Monday, Egypt's President Abdel-Fattah El-Sisi claimed that the advancement of human rights is a top national priority for the country's Vision 2030.
"These (changes) are effective from now as your constitution", commission chairman Lasheen Ibrahim told a news conference broadcast on state TV.
"Rather than being a reflection of actual data, the announced 44 percent turnout is more likely an attempt to portray this as the most legitimate constitutional referendum, as it has the highest turnout ever reported", she said.
Nearly 27 million votes were cast out of an eligible base of 61 million voters.
Opposition parties had urged a "no" vote, but they have little sway in parliament, which is packed with el-Sisi supporters and overwhelmingly approved the amendments.
El-Sissi, who has been in power since 2014 after he led the military overthrow of an elected but divisive Islamist president, thanked the people of Egypt on Twitter shortly after the results were announced.
The amendments, which were approved by Egypt's parliament last week, will extend el-Sisi's current term to six years from four and allow him to run again for a third six-year term in 2024.
"The referendum on the constitutional amendments", he added, "will be recorded with pride in the history of our great nation".
The local media is also dominated by pro-government commentators, and the authorities have blocked hundreds of websites, including many operated by independent media and rights groups.
Two worldwide advocacy groups - Human Rights Watch and the global Commission of Jurists - had urged the Egyptian government to withdraw the amendments, saying they placed the country on a path to more autocratic rule.
Human rights groups have spoken out against the changes and the political climate surrounding the vote. Voters were only given days to digest the changes to 20 articles.
"There will be risky repercussion from the ruling regime as we will see more repression and restrictive policies", he told the Associated Press news agency.