A week after being compared to Jonah Lomu by Sir Clive Woodward in response to a bulldozing man-of-the-match display against Italy, Cokanasiga is unable to even secure a place on the bench for the game with Scotland tomorrow.
Taking his place in the number 14 jersey is Jack Nowell, who has recovered from a shoulder stinger injury, with Ben Te'o picked as replacement threequarter cover.
"We have had a good preparation and the side is going to be in a great state to play against Scotland on Saturday".
"He'll feature very strongly in our plans for the future, but we just feel this week that Jack Nowell is our best player in that position".
'We've got a good plan in place for him [Cokanasiga].
Cokanasiga's destination is the World Cup in Japan this autumn and Jones's explanation, which he expects the 18-stone Bath wing will come to appreciate over the next six months, was that there is a masterplan...
Elsewhere Henry Slade returns in the centres to partner Manu Tuilagi.
In the forwards, prop Ben Moon and flanker Mark Wilson replaced Ellis Genge and Brad Shields, respectively.
Starting number nine Ben Youngs will become England's most capped scrum-half on Saturday, overtaking Danny Care with his 85th outing.
They did beat England in Edinburgh past year when they outmuscled Jones's team at the ruck and the Australian said he expected a different scenario on Saturday after overseeing a massive improvement in that area, and in their discipline.
But if the Welsh lose, England will take the title instead if they beat the Scots.
They should go for that gap, sell that outrageous dummy and make that long, floated pass - just like the glorious one from Finn Russell to Huw Jones the last time the two sides met.
"If we impose our game on Scotland it'll be pretty tough for them", said Jones, whose team finished fifth last season after losing their last three games and then lost two in a row against South Africa.
"With young players, particularly in this environment, you've got to look after them", England's head coach said.