For the same match past year, Wales made 10 changes and gave the captaincy for the first time to Taulupe Faletau and they won at home by a convincing 38-14.
Warren Gatland is hoping his players can write their names into the history books with a win over England at the Principality Stadium on 23 February.
Stand-in captain Jonathan Davies was frustrated.
Italy scored the only try of the first half to trail 12-7 at halftime and Wales didn't score a try until the 53rd minute and finished with only two, but it was enough to notch an 11th successive victory, tying the Welsh record set 109 years ago.
"Italy will be hurting after last weekend but they are a different proposition in Rome".
The latest Italy Vs Wales team newsWhat happened in the same fixture in 2018?
Centre Jonathan Davies captains his country for a first time - regular skipper Alun Wyn Jones is on the replacements' bench - as Wales head coach Warren Gatland makes 10 changes and one positional switch from the side that beat France last week.
Wales flew down the right touch then attacked down the left, where fullback Liam Williams drew the last man to send Adams into the corner for their first try. We didn't play that well but, as I said to the boys in the changing room, we'll take the win, move on and start thinking about England.
ITALY - J Hayward; E Padovani, M Campagnaro, L Morisi, A Esposito; T Allan, G Palazzani; N Quaglio, L Ghiraldini, S Ferrari; D Sisi, D Budd; S Negri, A Jurgens Steyn, S Parisse.
Wales finally hit back with converted tries by Josh Adams and Owen Watkin to make the result safe with 10 minutes to go. Flanker Aaron Wainwright and scrumhalf Aled Davies received their first Six Nations starts.
Wales' Liam Williams, top, is tackled by Italy's Luca Morisi during the Six Nations rugby union worldwide between Italy and Wales, at Rome's Olympic Stadium, Saturday, Feb. 9, 2019.
The son of Wasps rugby director and former Wales prop Dai Young, Thomas Young has impressed in the English Premiership this season.
Ireland captain Rory Best praised the strong performance of Carbery, who replaced Sexton and played an influential role during the second half after throwing the intercepted pass that led to the only Scottish try.
Italy's Angelo Esposito, left, challenges for the ball Wales' Owen Watkin during the Six Nations rugby union global between Italy and Wales, at Rome's Olympic Stadium, Saturday, Feb. 9, 2019.