"We're looking at the operating rules around the Menindee Lakes and what we can do".
Also worrying will be if further wildlife loss succumb from heat exhaustion, he said.
"In droughts, rivers are the last resort for so much of our wildlife", Professor Kingsford said.
Millions of fish are thought to have died after a blue-green algae event in recent days.
Niall Blair, NSW's fisheries and regional water minister, blamed the deaths on drought.
Labor leader Michael Daley called for a special commission of inquiry into the "ecological catastrophe" at Menindee.
In a video that has been viewed almost 4 million times, Menindee resident Dick Arnold and rancher Rob McBride say the fish kills are "a manmade disaster".
Mr McBride said: "This is nothing to do with drought, this is a man-made disaster".
"The [Coalition parties] have been repeatedly warned by far west residents, community groups, scientists and Labor that their water policies would cause devastation on the Darling River".
Taxpayers have stumped up more than $13 billion to restore the health of the basin. "Without more water available to flow through the system, it is possible more fish will die during summer".
The immediate cause of Menindee's calamity was a change in temperatures that killed much of the blue-green algal bloom on that part of the river.
Dying algae robbed the water of oxygen and the fish suffocated. "We can not be indifferent to the ecological impact and the effect on local residents who live along the river".
"This is the result of draining the Menindee Lakes twice in four years, killing the system".
Mr Blair said he had requested that Department of Primary Industries and WaterNSW prepare an urgent report on the fish kill and clean up. He added the SDL project at Menindee, which aims to save 105 gigalitres a water a year, must proceed.
"On the Barwon-Darling, the impact on cotton production is even more devastating with zero hectares of cotton being grown in Bourke this season, down from 4,000 hectares the year before", the general manager of Cotton Australia, Michael Murray, said. "You would blow up the [Murray-Darling Basin] Plan".
The state's independent MP, Jeremy Buckingham, travelled to the area after the farmers' video went viral, and said he vomited when he saw the scale of the deaths.
Buckingham managed to get in a couple of jabs, criticising the management of the Murray Darling basin by the National Party and the "desecration of the river by cotton irrigators upstream", before the stench forced him to run off screen to loudly retch into nearby bushes. "Sadly, it is entirely predictable for those of us that have been warning about the raft of problems plaguing the implementation of the Murray-Darling Basin Plan".