In 2002, Israel began to build a security barrier separating Jerusalem from the rest of the West Bank in an apparent bid to bolster security following the Second Intifada; Palestinians dubbed the undertaking the "apartheid road", and the unveiling of another similar project is now causing controversy.
There are dozens of segregated and settler-only roads across the occupied Palestinian territory, but Route 4370 is the first of its kind to have a wall - half concrete, half fence - separating Palestinians from Israelis.
Israel's Public Security Minister Gilad Erdan said the road would ease heavy traffic for settlers in the area while helping Israel overcome "security challenges".
But Palestinians travelling between the north and south of the West Bank would have to change course and some Palestinian villages would find themselves further isolated from Jerusalem, said Tatarsky. Other images showed the assailant being taken away by troops on a stretcher.
The long-term goal is to provide settlers with another route to allow them to access Jerusalem more directly, said Aviv Tatarsky of Israeli NGO Ir Amim, which opposes settlement expansion.
The Palestinian Foreign Ministry slammed the new road as "emphasizing Israel's approach aiming to undermine prospects for geographical and demographic contiguity of the West Bank".
For Tatarsky, the road is also part of a push to incorporate Israeli settlements near Jerusalem more closely into the city, he said.
If implemented, the southern West Bank would be completely cut off from the north, making a future contiguous Palestinian state almost impossible.
Israel says the barrier is necessary for security, but for Palestinians it has become a symbol of the occupation.
Ahmed Mohammed al-Qaysi, a Palestinian driver for the Al-Zaim local council, does not have permission from Israel to cross the separation barrier and enter Jerusalem, like many Palestinians in the West Bank.
Israeli NGO Ir Amim said in a press release that the road was the "brainchild" of former Israeli Prime Minister Ariel Sharon, and was created to "solve the dilemma of E-1 splitting the West Bank into northern and southern enclaves by using road infrastructure to preserve a semblance of contiguity between Ramallah and Bethlehem".