The researchers in Brazil reported that the uterus was ischemic - meaning, off a blood supply - for nearly eight hours, essentially double the reported time from any of the living donor transplants.
Women who would be candidates for a uterus transplant would have absolute uterine infertility, meaning they don't have a uterus or that it is too damaged to support a pregnancy.
The first successful childbirth following uterine transplant from a living donor took place in 2013 in Sweden, and there have been 10 others since then.
They say that 10 other uterus transplants from deceased donors were performed in the U.S., Turkey and Czech Republic, but none of them resulted in live births. Of the 10-15 per cent of couples with infertility problems, one in 500 women have uterine abnormalities. "While uterine surrogacy is legal in the us, this offers an option, albeit an extreme and expensive one, to women who want to carry their own baby".
The baby's birth suggests that more women who suffer from uterine infertility - including those who have undergone hysterectomies for reasons ranging from cancer to endometriosis - may be able to take advantage of the procedure moving forward, says paper co-author Dr. Dani Ejzenberg, who oversaw the case and is a medical faculty member in the division of obstetrics and gynecology at the University of São Paulo.
He describing the procedure as a "medical milestone". "The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population".
The recipient had Mayer-Rokitansky-Küster-Hauser syndrome, which affects about one in every 4,500 women and results in the vagina and uterus (womb) failing to form properly. The donor was 45-years-old and had borne three children in her lifetime before dying of a stroke.
Although uterus transplants are a growing area of medicine, they remain highly experimental and are very hard surgeries to complete.
Ejzenberg said that finding a living donor could also be hard, while coordinating operations was logistically challenging.
To prevent her body from rejecting the new organ, the woman was given five different drugs, along with antimicrobials, anti-blood clotting treatments, and aspirin.
Five months after the surgery, the medical team observed no signs of rejection, noting that ultrasound scans were normal and the recipient experienced regular menstruation. Fifteen were fertilised, with 8 resulting in embryos that were subsequently preserved for later implantation. Ten days later, doctors delivered the good news: she was pregnant.
The woman's pregnancy was normal, and doctors performed a Caesarean section on December 15, 2017, after about 36 weeks (a full term is about 40 weeks).
No. In order to keep the uterus after birth, the mother would have to continue taking immune system suppression medications which can pose risks.
The study was welcomed by British fertility expert Dr Srdjan Saso, part of the Womb Transplant UK team, who said: "Our hope, as we plan to kick-start the UK programme at the beginning of 2019, is for the deceased donor uterine transplant programme to grow alongside its "live donor" counterpart".