"I've made the flawless record and now I can leave at the very top", Buble said.
"I don't have the stomach for it anymore".
Although Noah's now in remission, the entire experience has changed Bublé's outlook on life, particularly his feelings toward being a celebrity.
OK! online has contacted a representative for Michael Bublé for comment.
He added to the Daily Mail's Weekend magazine: "I decided I'll never read my name again in print, never read a review, and I never have". My perception of life'.
It seems he has also been on a life-changing personal journey which forced him to recognise he had been unhappy with his life and career even before Noah's diagnosis. "When this bad news came in I realized I wasn't having fun in the music business", he shared.
Speaking about his son's diagnosis he said, "You just want to die".
Michael Bublé has revealed he is retiring after giving his "last ever interview". I don't know if I can get through this conversation without crying.
Michael's son Noah, 5, was diagnosed with hepatoblastoma, a liver cancer, at just three years old. "The diagnosis made me realise how stupid I'd been to worry about these unimportant things".
"It wasn't as straightforward as, 'My son's recovered, I should make an album'. I was embarrassed by my ego, that it had allowed this insecurity".
"And I've never lost control of my emotions in public", he said.
During an emotional "last interview" Michael opened up about the devastating impact Noah's illness had on the couple.
"It was then that I realised I'd missed making music". It still sucks. What we went through was the worst possible thing that you could hear as a parent, and as maybe a human being. "I'd much rather it'd have been me".
He said: "More times than people could understand, some days we wished we didn't wake up". Michael also shares children Elias, 2, and 2-month-old Vida, with his wife.
Michael had similar heartbreaking words just last week.