He broke the previous world record set in Berlin by Kenyan Dennis Kimetto in 2014 by 1 minute and 18 seconds an improvement that had not been witnessed in fifty years.
By the half way mark, Kipchoge had completely imposed himself on the race with chasing compatriot Wilson Kipsang and Amos Kipruto nowhere in sight.
Kipchoge ran his first 5km in 14:24, a whole 1:26 ahead of world record pace, and reached 10km in 29:01.
"I had a great belief that I would run a World record but I dint know I would run 2:01".
The 2003 World 5,000m champion build a 45 seconds inside Kimetto's world record when passing the 35km mark in 1:41:03 before cruising past the 40km in 1:55:32 against Kimetto's 1:56.32. "Berlin forever! I shall come back here next year".
"I lack words to describe this day", said Kipchoge. I had to focus on the work I had put in in Kenya and that is what helped push me'.
With his 1:18 demolition of the previous record on Sunday- almost three seconds faster per mile than Kimetto's mark- Kipchoge has now reached a summit that seems befitting of a man who has rarely been challenged in the event.
Kipchoge started off with a sizzling pace and quickly shook off his biggest opponent, Wilson Kipsang, to make it a one-man race.
And on a pleasant autumn day in Berlin the 33-year-old lived up to that billing - and more - as he proved beyond doubt that he is the greatest long distance runner in history by obliterating the marathon world record. Cherono won in 2:18:11, breaking the previous course record (2:19:12, Mizuki Noguchi, 2005) by over a minute.
The marathon had initially given his unofficial time as 2 hours, 1 minute and 40 seconds, then adjusted it by one second.
New York Times in a publication on Kipchoge wrote: "Elite distance runners generally run no more than two marathons each year". "That's what I believed (breaking World Record) and I am happy for it". Ironically, it took a world record setting run by Kipsang in 2013 in Berlin to beat Kipchoge in what was just his second marathon since moving from the track.
He has notched up 10 wins from the 11 marathons he has raced, winning three times not only in Berlin but also London, with victories in Rio for Olympic gold as well as in Hamburg, Rotterdam and Chicago.