The 100 came up in just 40 balls, making it the fastest ever CPL T20 century that also contained a record 13 sixes.
Having blasted a Queen's Park Oval record 195/6 in the opening game of the tournament 48 hours ago, TKR obliterated that mark with their 223/6. Dwayne Bravo shuffled his bowling options but could not stop the flow as six after six rained down on a disbelieving crowd in Trinidad.
Russell found a willing ally in Kennar Lewis, who made 52 from 35 in a 161-run partnership.
But such was the nature of the single-handed transformation Russell wrought upon this game that this must surely stand alone among all individual T20 performances.
A power-packed Knight Riders batting line-up sent 14 sixes over the boundary ropes - astonishing at the time but later put firmly in perspective by Russell's one-man wrecking mission.
Earlier, vicious onslaughts from the duo of Colin Munro and Brendan McCullum led the Knight Riders to what had appeared to be an unreachable 223 for 6, particularly with the way the Tallawahs began in pursuit of the target.
Having struggled to 7 not out from his first 12 deliveries, McCullum smashed a further 49 from his next 14 balls to propel the score well beyond 200.
It would turn out to be only the very start of Russell's game-changing night. Lynn was caught by Russell off the bowling of Krishmar Santokie after making 46 off 27 balls but there was little respite as McCullum was the next man in.
His 13th six sealed the match, when five runs had been required from four balls.
And, when American seamer Ali Khan took three wickets in six balls across two overs, including trapping Ross Taylor lbw for 1 and Johnson Charles was struck on the pads by spinner Fawad Ahmed for 21, Jamaica looked in trouble at 41-5. It seemed likely to be a one-sided contest when Powell was dismissed for a single run by Shannon Gabriel but up stepped Russell.
But in strode Russell to be promptly dropped by Ali Khan at deep midwicket.
Trinbago Knight Riders v St Kitts & Nevis Patriots (8pm), Queen's Park Oval.