Jones and Pete Kozma ripped RBI doubles to tie the game. They had lost their last 11 games to their division rival.
UP NEXT: The teams finish a three-game series Wednesday afternoon with Clevelands Trevor Bauer (2-3, 3.00) facing a Tigers pitcher to be named.
Davis, though, hit a two-run double off Reininger in the sixth to give Cleveland a 7-3 lead, and he scored on Ramirezs double off Hicks glove at first.
Yarbrough allowed one run on five hits and three walks with four strikeouts in five innings. Chaz Roe, Jonny Venters, Sergio Romo, Jose Alvarado and Alex Colome combined to throw four scoreless innings in relief.
The Tigers fought their way back into the game, culminating in a dramatic seventh inning in which they scored five runs, the last two coming against Indians top reliever Andrew Miller.
Manaea (5-4) pitched the first no-hitter against the Red Sox in 25 years in his last start against them at home on April 21, striking out 10 batters in a 3-0 victory. He had only two home runs and five RBIs for his career before matching both those totals in one game Monday. The Tigers have still won three of their last four. He led off the game with a solo homer, his 13th, and added a single and a double.
Atlanta's other home runs came from Tyler Flowers, a two-run shot in the third, and Jose Bautista, a two-run homer in the fifth.
Hicks had a leadoff single and drew a bases-loaded walk during a five-run uprising in the seventh inning.
Villar, added when Ryan Braun was scratched due to right mid-back tightness, homered in the ninth inning after singling and scoring in the second and seventh innings.
Mike Fiers (4-2) allowed a run and three hits for Detroit in six innings. It is also 4-1-1 in the Tigers' last six overall, 5-2 in their last seven against winning opponents, and 18-7-1 in their last 26 at home against winning opponents.
Justin Anderson, who inherited the closer role for Los Angeles when Keynan Middleton hurt his right elbow, gave up two singles in the ninth inning sandwiched around a double play to earn his first major league save.
PADRES 4, ROCKIES 0: In San Diego, right-hander Jordan Lyles came within five outs of the first flawless game in Padres history before allowing a single to Trevor Story.
The blast made a victor of left-handed starter Tyler Anderson (3-1), who allowed the Padres four runs (three earned) on seven hits and a walk with three strikeouts in 5 2/3 innings. The Rockies hit only two balls out of the infield before Story singled. Wade Davis earned his 15th save. McCann hit an RBI double, and Dixon Machado's groundout knocked in a run.
Utility man Niko Goodrum was the star on Monday, ripping two homers and driving in five runs. He allowed four runs and nine hits, including home runs by Tucker Barnhart, his third, and Scott Schebler, his fifth.