The agency announced that within the next 72 hours, air-to-surface missiles or cruise missiles could be used in Syria. Trump said late Monday that the USA will respond "forcefully" to a suspected chemical weapons attack by Syrian President Bashar al-Assad's regime over the weekend, after suggesting earlier that Russian President Vladimir Putin may share responsibility.
According to the Flightradar24 portal, now in the sky over Syria, air transportation has been practically ceased.
Tim Clark, president of Dubai-based Emirates airline, said at a press conference in Hamburg that the carrier is studying how to reroute planes away from areas near Syria.
There has been heightened awareness by regulators and airlines of the risks that conflict zones pose to commercial jets since Malaysia Airlines flight MH17 was shot down by a surface-to-air missile over Ukraine in 2014, killing all 298 people on board. The notification by Eurocontrol referred to an area wider than what is now controlled by Damascus but did not include the entire country.
A spokesman for Germany's Lufthansa said on Wednesday its airlines were aware of the Eurocontrol warning and were in close contact with authorities.
Europe's air traffic controllers, Eurocontrol, have issued a Rapid Alert Notification for airlines travelling in the Eastern Mediterranean over potential air strikes on Syria.
Ryanair flights are "operating normally".
The Nicosia flight information region named in the Eurocontrol statement covers the island of Cyprus and surrounding waters, according to a map on the agency's website.
In 2017, North Korea tested missiles without warning, leading many airlines to change flight routes to avoid areas around the Sea of Japan.
"Russia vows to shoot down any and all missiles fired at Syria".