The Dutch centre-half has not been a complete success since his £75m move from Southampton but he is a giant, he has a presence and he has a reputation for standing up in the big games and performing.
That 18-point gap is no coincidence, however.
"The Champions League is a really tough tournament and every single game is really special and difficult".
Another potential blow for Jurgen Klopp is that the first leg is at Anfield.
"While recognising that some supporters feel they can add to the atmosphere of the occasion, the use of flares and other pyrotechnics at and around football matches is a concern".
But it was the events in the tunnel of the loss at the DW Stadium that have sparked concern. With reports that the FA are concerned that his team are becoming badly behaved, the spotlight is likely to fall upon the players in their upcoming high-profile matches.
Both league tussles will leave the losing sides with excuses for why they were turned over, but the European aggregate-style score of 8-4 would naturally be more than enough to carry City through, were it repeated next month. Of course he will.
Indeed, Roma sporting director Monchi had said City were the team to avoid, while plenty of Barcelona fans on Twitter had said that the Blues were the team they most feared. It could be a breeding ground for tempers to flare and City haven't been shy when it comes to sticking up for themselves recently.
The Camp Nou sees Barcelona run wild and grab a 3-0 lead in the first leg. Roma must out Barca Barca with a repeat of the Catalan giants heroics against PSG last year but can only get a respectable 1-1 draw at the Stadio Olimpico. I cannot see the reigning champions making the same mistakes as Mauricio Pochettino's team over two legs. At home, they still carried the air of invincibility that Roberto Mancini's team had developed.
"I didn't have a special target", he explained.
Gundogan has played a part in Man City's hugely impressive season, which could end with silverware on three fronts if they can maintain their current form.
Mohamed Salah has played down the task facing Liverpool in their Champions League quarter-final against Manchester City, claiming the Reds fear no opponent.
It's fair to say that hardly anybody on the continent wanted to face Guardiola's men.