Australian researchers identify drug to reverse alcohol effect

  • by Laura Grandis
  • in Médecine
  • — Fév 10, 2018
Share:

An anti-anxiety drug has been found to have the ability to reboot our brains and reverse the negative effects alcohol has on our brains, according to researchers at the Queensland Univesity of Technology.

Tandospirone, a drug with anxiolytic and antidepressant properties, may help reverse neurogenic deficits caused by chronic alcohol consumption, according to a study in Scientific Reports.

Tandospirone acts selectively on a serotonin receptor (5-HT1A).

Alcohol has always been known to cause damage to the brain but findings of the new study, which were published in the journal Scientific Reports, showed for the first time that tandospirone could reverse the deficit induced by alcohol consumption on brain neurogenesis, the process by which new neurons are formed.

Additionally, the drug, which is closely related to the nonbenzodiazepine buspirone, was shown to be effective in reducing anxiety caused by alcohol withdrawal.

"We know that with heavy drinking you are inhibiting your ability to grow new neurons, brain cells".


Professor Bartlett, who is based at the Translational Research Institute, said the discovery by study co-authors QUT postdoctoral research fellows Dr Arnauld Belmer and Dr Omkar Patkar came about serendipitously after research started in a different direction. Alcohol is specifically very damaging for neurons.

"This opens the way to look at if neurogenesis is associated with other substance-abuse deficits, such as in memory and learning, and whether this compound can reverse these".

"It is commonly used there and shown to be highly effective in treating general anxiety and well tolerated with limited adverse effects", Bartlett says.

Bartlett said that tandospirone does not just show promise in helping reduce binge drinking.

The researchers are constantly looking at new treatment strategies for alcohol abuse and addiction, which is characterised by extended periods of heavy alcohol use, binges and abstinence, and anxiety and depression which contribute to relapse.

Share:

IN CASE YOU MISSED IT

RELATED NEWS

Kangana Ranaut on Manikarnika controversy: Fringe group is defaming Rani Laxmibai
Mr Mishra said all issues have been resolved with the film producer. Thus, the producer came and met me and replied to my queries.
2/10/2018

School holds prayer vigil for teen who died from flu
Across the country, doctors are seeing more cases, hospitalizations and deaths from flu, and there's no sign it's letting up. Another health center, Loma Linda University Medical Center, had to use a tent that they normally designate for disasters.
2/10/2018

Caesars Entertainment (CZR) Shareholder Cornerstone Capital Management Holdings Has Decreased Stake by
Since January 30, 2018, it had 6 insider purchases, and 0 insider sales for $414,397 activity. $73,039 worth of TCP Capital Corp. (NASDAQ:TCPC) to report $0.38 EPS on February, 27.They anticipate $0.07 EPS change or 15.56% from last quarter's $0.45 EPS.
2/10/2018

House passes short-term bill to fund government
House Speaker Paul Ryan, R-Wis., pledged on the House floor early this morning that he also meant to address immigration . The bill faced similar opposition in the House from fiscal conservatives who saw it as a broken promise to their base.
2/10/2018

Comparable Company Analysis: Prospect Capital Corporation (PSEC), The New York Times Company
Callahan Advsrs Limited Liability holds 0.02% of its portfolio in Prospect Capital Corporation (NASDAQ:PSEC) for 12,000 shares. The total amount of shares outstanding is 365.48 million, giving the company a market capitalization of about 2.30 billion.
2/10/2018

Frenchman Abraham Kiprotich Emerges Victorious At The Lagos City Marathon
He also announced additional cash reward for Nigerian athletes who finished top in the male and female categories as well as young athletes.
2/10/2018

SPDR Bloomberg Barclays High Yield Bond (JNK) Enters Oversold Territory
ILLEGAL ACTIVITY WARNING: This news story was originally published by StockNewsTimes and is owned by of StockNewsTimes. Symmetry Partners LLC increased its stake in SPDR Barclays Capital High Yield Bnd ETF by 9.7% in the 4th quarter.
2/10/2018

Lebron James, Cleveland's real GM, approves of the Cavaliers' trades
Thursday's wild National Basketball Association trade deadline has had long-reaching ramifications, extending far beyond the pros. Hill and Hood are sharp shooters from 3 point range, and LeBron can set them up with his power drives and kick out passes.
2/10/2018

Rand Paul was right
Paul's protest forced Congress to miss a midnight deadline for passing a funding measure to keep the government operating. USA stocks plunged on Thursday on heavy volume, throwing off-course a almost nine-year bull run.
2/10/2018

Banco Bradesco (NYSE:BBD) Upgraded by JPMorgan Chase & Co. to "Overweight"
JPMorgan Chase & Co. raised Banco Bradesco from a "neutral" rating to an "overweight" rating in a report on Monday, January 22nd. Banco Bradesco S.A. (NYSE:BBD) now has a Weekly Volatility of 4.88% percent while its Monthly Volatility is at 3.15% percent.
2/10/2018

Decreases Holdings in Liberty Global plc
The stock of Liberty Global plc (NASDAQ:LBTYA) earned "Outperform" rating by RBC Capital Markets on Monday, November 9. Shares buyback programs are typically a sign that the company's board of directors believes its stock is undervalued.
2/10/2018

Mike Pence didn't snub North Koreans deliberately, officials say
There will be no Russian flag though, and their uniforms will have a few extra words: "Olympic Athlete From". S. pressure campaign by expelling North Korean "financial facilitators and trade reps".
2/10/2018

'Child's Play' Is Coming to TV From Movie Series Creator
Speaking with Bloody Disgusting , Mancini spoke a little about what to expect: "We plan to use " Child's Play " in the title". Kirschner added: "I'm incredibly excited about the series and to explore a world in which we've never done before".
2/10/2018

Des blessés dans un accident impliquant le cortège de Trudeau
Selon la chaîne américaine ABC News, un véhicule utilitaire sport a heurté un policier à moto qui tentait de bloquer la circulation en amont du convoi transportant M.
2/10/2018

South Korea's Moon hosts talks with North Korean leader's sister
US Vice President Mike Pence arrived in the South yesterday and is also scheduled to attend the opening ceremony in Pyeongchang. Moon has looked to the games as an opportunity to pursue a diplomatic opening with the North - a move Pence cautioned against.
2/10/2018