The Belgian worldwide has taken another step forward since Pep Guardiola took over as manager.
This Saturday the pair meet again at Stadium MK with points vitally important at this stage as well as bragging rights.
With that being the case, Fred is one of their best players, if not the best and is now a target for Manchester City who have made their move. It nearly reminds me of Mauricio Pochettino's approach when Spurs went to the Etihad earlier in the season, where they lost but they lost playing their way rather than setting up to get a draw.
The Blues have returned winless in last three matches in all competitions.
That is something he will not get this year, when Belgium are expected to make a strong challenge at the World Cup in Russian Federation, with one of their group matches being against England.
Liverpool will be out for revenge after the humbling they received at the Etihad earlier this season, and in the form they are in, a good performance and the backing of their home fans could help them over the line.
"There was a time, when he was at Dortmund, when I was still in the academy that I could have gone there from Schalke".
Manchester City have not lost in the Premier League since April
I know that once the players are out there on the pitch, nothing else maters-especially not history.
In an interview with former Liverpool player Phil Thompson on Sky Sports, Klopp said he was approached to become United boss before they appointed Louis van Gaal for the 2014-15 season.
Even the German club's Sporting Director, Klaus Allofs, described the offer from City as "astonishing". The addition of Virgil van Dijk to their Premier League squad will make them stronger at the back and he will get another opportunity to impress against the league leaders. "Of course we can lose the title because you never know what is going to happen in the next 13 or 14 games you have to play". The Chilean's contract with Arsenal runs out at the end of the season, and the club will definitely want to cash in, rather than letting him go for free.
These two teams have had an extremely close rivalry in recent years. However, this match is likely to be open and that will play into the hands of the midfielder. "I'm 100 per cent confident", he said.
De Bruyne is the master of the pass before the pass and his ability to find teammates is superior to any GPS system.
"And he has better vision than Colin".
This season, the Reds are currently fourth in the league thanks to the form of Mohamed Salah, Roberto Firmino, Sadio Mane and the now-departed Philippe Coutinho, and have qualified for the last 16 in the Champions League, where they will face FC Porto.