With Brissett showing flashes in his limited work in Week 1, many were calling for the 2016 third-round pick to get the start against the Cardinals.
PALMER ON REBOUND: Arizona quarterback Carson Palmer had one of the worst games of his career in the season opener, going 27 of 48 passes for 269 yards with a touchdown and three interceptions. You can't have it on offense.
The Bengals fired offensive coordinator Ken Zampese on Friday, marking the first time the organization has fired a coordinator during the season in the team's history. The Cardinals allowed 26 straight points to fall behind 35-17.
The Colts are fortunate as the Cardinals enter this game without their best player after David Johnson went down with a wrist injury. The Cardinals won't win the division, I still think that will go to Seattle, but a wild-card berth is still very possible in Arizona this year.
Arians devoted two chapters of his book - "The Quarterback Whisperer" - to his awesome 2012 season with Luck and the Colts, and he's been rooting for the quarterback's healthy return.
They should start the game by pounding the ball down the Cardinals' throat with running back's Frank Gore and Marlon Mack. He threw two of his three interceptions in Week 1 between the hashmarks, and his accuracy waned significantly with throws that traveled beyond 10 yards.
With Andrew Luck out, I have zero faith in the Colts, and are a must-fade until he returns to the lineup. Arians has worked with many skilled quarterbacks during his National Football League tenure, from Peyton Manning and Ben Roethlisberger to Luck and Palmer.
"It changes drastically", Palmer said.
"It'll be different than going to the (scouting) combine", Arians said Wednesday.
Teams like the Browns and Jaguars have spent decades looking for a good QB. "He had a great practice today, and he can put things behind him and move forward as good as anybody I've ever been around".
"I think it's really important because it gets people's spirits back up after you've been inside for so long and so afraid", Welsh said. "It can't be here fast enough".
This game between the Cardinals and the Colts features two teams that looked very bad in Week 1.
"We're just in a bounce-back mentality", he said.
"We haven't had any injuries over there other than Robert so we should play better defensively for four quarters", Arians said. That's what needs to happen for a team down so many pivotal players to have a chance on Sunday.
According to Pro Football Focus, Reddick, the 13th overall pick in the 2017 NFL Draft, scored the second-highest grade among rookie linebackers, receiving a mark of 80.9 - the highest of any Cardinals player.