We know the Blues have designs on a top four spot - something which can not be scoffed at, especially after Leicester City showed anything is possible by winning the 2015/16 league title.
The departure of Lukaku certainly guarantees Ramirez of a chance to play as the centre-forward of the side in the upcoming season and the Spaniard will be keen to improve on his already impressive numbers from the last season.
Everton Manager, Ronald Koeman, has admitted that it is a hard task for the club to replace former striker, Romelu Lukaku, who now plays for Manchester United.
"We still have three players out on long-term injuries in Seamus Coleman, Yannick Bolasie and Ramiro Funes Mori, but they are doing well", Koeman told the club's official website.
Stephen Ireland is "a matter of weeks" away from a return while Ibrahim Afellay is still sidelined, having undergone knee surgery. His last win was in 2009 as Manchester City manager.
"In the Premier League if you think you have an easy start you will pay for that".
Only Frank Lampard and Alan Shearer (8) have scored more goals on Premier League opening day than Rooney (7).
Veteran Stoke striker Peter Crouch has been involved in 10 goals against Everton in his Premier League career (six goals, four assists) - only against Aston Villa (11) has he been involved in more.
Everton will grind out a hard-fought win in this one.
Everton are ready to do their talking on the pitch after a summer in which they have made the size of their ambitions clear. "I heard some rumours that the talks broke down but we are still in negotiations with Swansea".
Having said that I'm backing them to kick the season off with a win against a Stoke side I fear will struggle having lost Marko Arnautovic to West Ham.